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鐘意食豬潤麵入:基因技工程新突破,未來可由豬隻生產器官供人類使用
http://www.bbc.com/news/health-40886600
Tests identified 25 Pervs - porcine endogenous retroviruses - hidden in the pig's genetic code.
Experiments mixing human and pig cells together showed those viruses could escape to infect human tissues.
But the researchers then used the game-changing gene-editing technology Crispr to delete the 25 Pervs.
It then took cloning technology, the same used to create Dolly the sheep, to place the genetic material from those cells into a pig's egg and create embryos.
The complex process is inefficient, but 37 healthy piglets have been born.
"These are the first Perv-free pigs," Dr Luhan Yang, one of the researchers from Harvard University and the spinout company eGenesis, told the BBC News website.
They were also "the most genetically modified [animals] in terms of the number of modifications", he said.
If xenotransplantation - using organs from other species - works, then it has the potential to alleviate long waits for a transplant.
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